| 品牌 | SCRSTANDARD | 供貨周期 | 現貨 |
|---|---|---|---|
| 應用領域 | 醫療衛生,化工,生物產業,制藥/生物制藥 |
核苷酸是一類由嘌呤堿或嘧啶堿、核糖或脫氧核糖以及磷酸三種物質組成的化合物，又稱核甙酸。
戊糖與有機堿合成核苷，核苷與磷酸合成核苷酸，8種核苷酸組成核酸。核苷酸主要參與構成核酸，許多單核苷酸也具有多種重要的生物學功能，如與能量代謝有關的三磷酸腺苷（ATP）、脫氫輔酶等。
核苷酸是核糖核酸及脫氧核糖核酸的基本組成單位，是體內合成核酸的前身物。核苷酸隨著核酸分布于生物體內各器官、組織、細胞核及細胞質中，并作為核酸的組成成分參與生物的遺傳、發育、生長等基本生命活動。生物體內還有相當數量以游離形式存在的核苷酸。三磷酸腺苷在細胞能量代謝中起著主要的作用。體內的能量釋放及吸收主要是以產生及消耗三磷酸腺苷來體現的。此外，三磷酸尿苷、三磷酸胞苷及三磷酸鳥苷也是有些物質合成代謝中能量的來源。腺苷酸還是某些輔酶，如輔酶Ⅰ、輔酶Ⅱ及輔-酶A等的組成成分。
核苷（Nucleoside）是一類糖苷的總稱。核苷是核酸和核苷酸的組成成分。核苷都是由D-核糖或D-Z-脫氧核糖與嘧啶堿或嘌呤堿縮合而成。核苷一般為無色結晶，不溶于普通有機溶劑，易溶于熱水，熔點為160~240℃。由D-核糖生成的核苷稱核糖核苷，參與RNA組成，由D-α-脫氧核糖生成的核苷稱脫氧核糖核苷，參與DNA組成。
常見的核苷有：尿-嘧啶核苷（尿嘧-啶－1-β-D-呋喃核糖核苷）（見結構式a）、腺嘌呤核苷（腺嘌呤-9-β-D－呋喃核糖核苷）(b)、胞嘧啶核苷（胞嘧啶-1-β-D-呋喃核糖核苷）(c)、鳥嘌-呤核苷（鳥嘌-呤－9-β-D－呋喃核糖核苷）(d)、胸腺嘧啶核苷（胸腺嘧啶－1-β-D-2′－脫氧呋喃核糖核苷）(e)。
此外，核糖和脫氧核糖可與稀有堿基結合成相應的稀有核苷；還有碳－碳鍵連結在一起的假尿嘧-啶核苷(f)。
核苷可從水解核酸來制備。用吡啶水溶液、氧化鋁或酶促水解核糖核酸RNA，可得到核糖核苷；用氧化鋁或酶水解脫氧核糖核酸DNA可得到脫氧核糖核苷。核苷也可用化學方法合成。適當保護的核糖或脫氧核糖與堿基衍生物縮合，可得到相應的核糖核苷和脫氧核糖核苷。或在糖的C1上先形成碳－氮和碳－碳鍵，然后閉環成雜環堿基而得到核苷。
可從合成代謝、分解代謝及代謝調節三個方面討論。
合成代謝
核苷和核苷酸系列
核苷和核苷酸系列
| 貨號 | 英文名 | CAS |
| 核苷和核苷酸 | ||
| SCGC-150952 | GDP-L-Fuc.2Na | 15839-70-0 |
| SCGC-150953 | UDP-D-Xyl.2Na | 108320-89-4 |
| SCGC-150954 | UDP-L-Ara | 15839-78-8 |
| SCGC-150955 | UDP-D-Glc.2Na | 28053-08-9 |
| SCGC-150956 | UDP-D-Gal.2Na | 137868-52-1 |
| SCGC-150957 | GDP-D-Man.2Na | 148296-46-2 |
| SCGC-150958 | UDP-2-F-Glc.2Na | 67341-43-9 |
| SCGC-150959 | UDP-D-galactosamine.2Na | 17479-06-0 |
| SCGC-150960 | UDP-6-azido-6-deoxy-D-Glc.2Na | 537039-67-1 |
| SCGC-150961 | UDP-6-azido-6-deoxy-D-Gal.2Na | 868208-96-2 |
| SCGC-150962 | UDP-GlcNAc.2Na | 91183-98-1 |
| SCGC-150963 | UDP-GalNAc.2Na | 108320-87-2 |
| SCGC-150964 | UDP-GlcNTFA.2Na | 1355005-47-8 |
| SCGC-150965 | UDP-D-GlcA.3Na | 63700-19-6 |
| SCGC-150966 | UDP-D-GalA.3Na | 148407-07-2 |
| SCGC-150967 | UDP-GlcNAz.2Na | 1611490-64-2 |
| SCGC-150968 | UDP-GalNAz.2Na | 653600-61-4 |
| SCGC-150969 | UDP-4-F-GlcNAc.2Na | 705932-41-8 |
| SCGC-150970 | UDP-4-F-GalNAc.2Na | 727977-97-1 |
| SCGC-150971 | UDP-MurNAc.2Na | 927824-69-9 |
| SCGC-150972 | CMP-Neu5Ac.2Na | 149007-28-3 |
| SCGC-150973 | CMP-Neu5Gc.2Na | 176298-21-8 |
| SCGC-150422 | Guanosine diphosphate (GDP) | 7415-69-2 |
| SCGC-150423 | M7-GDP-IMZ | N/A |
| SCGC-150424 | 3'OMe-GDP | N/A |
| SCGC-150425 | M7-GDP-IMZ(3'OMe) | N/A |
| SCGC-150426 | (2'OMe-5'P-A)pG | N/A |
| SCGC-150427 | (2'OMe-5'P-A)pU | N/A |
| SCGC-150428 | (2'OMe-5'P-G)pG | N/A |
| SCGC-150429 | Morpholino A subunit | 956139-18-7 |
| SCGC-150430 | Morpholino C subunit | 956139-21-2 |
| SCGC-150431 | Morpholino T subunit | 956139-30-3 |
| SCGC-150432 | Morpholino G subunit | N/A |
| SCGC-150433 | UDP-α-L-Rha sodium salt | 1526988-33-9 |
| SCGC-150434 | GDP-6-deoxy-α-D-talose sodium salt | N/A |
| SCGC-150435 | UDP-2-deo-glucose sodium salt | N/A |
| SCGC-150436 | UDP-6-methyl-6-deoxy-D-glucose sodium salt | N/A |
| SCGC-150437 | UDP-3-methyl-glucose sodium salt | N/A |
| SCGC-150438 | UDP-4-F-6-D-glucose sodium salt | N/A |
| SCGC-150439 | UDP-β-L-arabinose sodium salt | N/A |
| SCGC-150440 | UDP-6-fluoro-6-deoxy-D-glucose | N/A |
| SCGC-150543 | Adenosine-5'-triphosphate | 56-65-5 |
| SCGC-150545 | Cytidine-5'-triphosphate (CTP) | 65-47-4 |
| SCGC-150546 | Guanosine-5'-triphosphate (GTP) | 86-01-1 |
| SCGC-150548 | m7Gpp | 531553-69-2 |
| SCGC-150549 | Pseudouridine 5'-triphosphate sodium salt | 28022-82-4 |
| SCGC-150550 | Uridine 5'-triphosphate (UTP) | 63-39-8 |
| SCGC-150249 | 2-Chloro-6-methoxypurine riboside | 15465-92-6 |
| SCGC-150000 | UDP-2-deoxy-α-D-galactose ammonium salt | N/A |
| SCGC-150586 | UDP-α-N-acetyl-D-galactosamine ammonium salt | 108320-87-2 |
| SCGC-150974 | DMT-dA(Bz) phosphoramidite | 98796-53-3 |
| SCGC-150975 | Da(Ac) phosphoramidite | 1027734-01-5 |
| SCGC-150976 | DMT-dC(Bz) phosphoramidite | 102212-98-6 |
| SCGC-150977 | DMT-dC(Ac) phosphoramidite | 154110-40-4 |
| SCGC-150978 | iBU-dC phosphoramidite | 110522-84-4 |
| SCGC-150979 | DMT-dG(iBU)-CE phosphoramidite | 93183-15-4 |
| SCGC-150980 | DMT-dG(DMF)-CE phosphoramidite | 330628-04-1 |
| SCGC-150981 | DMT-dT-CE phosphoramidite | 98796-51-1 |
| SCGC-150982 | DMT-2'-O-TBDMS-A(Bz)-CE phosphoramidite | 104992-55-4 |
| SCGC-150983 | DMT-2′-O-Me-rA(Bz) phosphoramidite | 110782-31-5 |
| SCGC-150984 | DMT-2'-F-dA(Bz)-CE phosphoramidite | 136834-22-5 |
| SCGC-150985 | DMT-2'-O-TBDMS-C(Ac)-CE phosphoramidite | 121058-88-6 |
| SCGC-150986 | Bz-rC phosphoramidite | 118380-84-0 |
| SCGC-150987 | DMT-2′-O-Me-rC(Ac) phosphoramidite | 199593-09-4 |
| SCGC-150988 | 2'-O-Me-Bz-C-CE phosphoramidite | 110764-78-8 |
| SCGC-150989 | 2'-F-Bz-dC phosphoramidite | 161442-19-9 |
| SCGC-150990 | 2'-F-Ac-dC-CE phosphoramidite | 159414-99-0 |
| SCGC-150991 | DMT-2'-O-TBDMS-G(iBU)-CE phosphoramidite | 147201-04-5 |
| SCGC-150992 | 2'-O-Me-iBU-G-CE phosphoramidite | 150780-67-9 |
| SCGC-150993 | DMT-2'-F-dG(iBU)-CE phosphoramidite | 144089-97-4 |
| SCGC-150994 | DMT-2'-O-TBDMS-U-CE phosphoramidite | 118362-03-1 |
| SCGC-150995 | DMT-2'-O-Me-rU phosphoramidite | 110764-79-9 |
| SCGC-150996 | 2'-O-Me-5-Me-U phosphoramidite | 153631-20-0 |
| SCGC-150997 | DMT-2'-F-dU phosphoramidite | 146954-75-8 |
| SCGC-150415 | DMT-dA(PAc) phosphoramidite | 110543-74-3 |
| SCGC-150416 | DMT-dG(IPAc) phosphoramidite | N/A |
| SCGC-150417 | DMT-dU-CE phosphoramidite | 109389-30-2 |
| SCGC-150418 | DMT-2'-O-Me-G(Ac)-CE phosphoramidite | N/A |
| SCGC-150419 | 5-Me-DMT-2'-O-Me-C(Bz)-CE phosphoramidite | 166593-57-3 |
| SCGC-150420 | 5-Me-DMT-2'-O-Me-C(Ac)-CE phosphoramidite | N/A |
| SCGC-150421 | 2'-F-dU-CE phosphoramidite | N/A |
| SCGC-150541 | 2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphorodiamidite | 102691-36-1 |
| SCGC-150542 | 2'-O-Methyladenosine | 2140-79-6 |
| SCGC-150544 | Bis(2-cyanoethyl) diisopropylphosphoramidite | 102690-88-0 |
| SCGC-150547 | Guanosine-9,17-N,N-(2-methyl-1-oxopropyl)-2',3'-diacetate | 163586-86-5 |
| SCGC-150551 | 2'-O-Methyluridine | 2140-76-3 |
| SCGC-150552 | 2'-O-Methylcytidine | 2140-72-9 |
| SCGC-150553 | DMT-2'-O-Me-dG(dmf) phosphoramidite | 128219-77-2 |
| SCGC-150554 | 5-Me-DMT-2'-O-Me-U phosphoramidite | 168611-18-5 |
| SCGC-150581 | 1-(2′-Deoxy-2′-fluoro-β-D-arabinofuranosyl)-thymine | 69256-17-3 |
| SCGC-150582 | 1-(2′-Deoxy-2′-fluoro-β-L-arabinofuranosyl)-uracil | N/A |
| SCGC-150583 | 1-(2′-Deoxy-2′-fluoro-α-L-arabinofuranosyl)-thymine | 1027764-72-2 |
| SCGC-150584 | 1-(2′-Deoxy-2′-chloro-β-L-arabinofuranosyl)-thymine | N/A |
| SCGC-150585 | 5-Fluoro-1-(β-L-ribofuranosyl)-uracil | 77210-26-5 |
| SCGC-150231 | Capecitabine | 154361-50-9 |
| SCGC-150232 | 2',3'-Anhydroinosine | 31766-13-9 |
| SCGC-150233 | 2'-O-Methylguanosine | 2140-71-8 |
| SCGC-150234 | Nicotinamide ribose | 1341-23-7 |
| SCGC-150235 | 2-Thio-6-azauridine | 27089-56-1 |
| SCGC-150236 | 2-Cl-IB-MECA | 163042-96-4 |
| SCGC-150237 | β-Pseudouridine | 1445-07-4 |
| SCGC-150238 | 3-Deazaadenosine | 6736-58-9 |
| SCGC-150239 | 5-Azidouridine | 1355028-82-8 |
| SCGC-150240 | 3'-Deoxy-2'-O-methyladenosine | 28361-08-2 |
| SCGC-150241 | 3'-Deoxyguanosine | 3608-58-0 |
| SCGC-150242 | 5-Bromouridine | 957-75-5 |
| SCGC-150243 | 5-Iodouridine | 1024-99-3 |
| SCGC-150244 | 5-Chlorouridine | 2880-89-9 |
| SCGC-150245 | 5-Azido-2'-deoxyuridine | 137359-50-3 |
| SCGC-150246 | Zebularine | 3690-10-6 |
| SCGC-150247 | 2,6-Dichloro-9β-(2',3',5'-tri-O-acetyl)-ribofuranosylpurine | 3056-18-6 |
| SCGC-150248 | 2-Chloroadenosine | 146-77-0 |
SCRSTANDARD屬于上海賽可銳旗下進口品牌，為科研工作者提供優質產品和真誠服務。
SCRSTANDARD品牌，產品種類齊全，主要包括以下幾類：
◆藥物化合物及其穩定同位素標記物 ◆氨基酸及其穩定同位素標記物
◆糖類及其穩定同位素標記物 ◆維生素及其穩定同位素標記物
◆脂類及其穩定同位素標記物 ◆肉堿及其穩定同位素標記物
◆膽汁酸及其穩定同位素標記物 ◆激素類固醇類及其穩定同位素標記物
◆植物提取物及其穩定同位素標記物 ◆聚合物及其穩定同位素標記物（包括GPC分子量標品，PEG衍生物等）
◆環境檢測標物及其穩定同位素標記物 ◆工業檢測標物及其穩定同位素標記物
◆農殘獸殘檢測標物及其穩定同位素標記物 ◆標準溶液及其穩定同位素標記物（色度標液, AAS, ICP, ICP-MS, IC等標液）
◆食品檢測標物及其穩定同位素標記物 ◆基質檢測標物及其穩定同位素標記物
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